Dear colleagues and friends It is our pleasure to invite you to the LS2 Annual Meeting 2018 with the topic "Metabolism & Signaling in the Life Sciences", held on the 12th and 13th of February, 2018 at the Amphimax/Amphipôle Campus of the University of Lausanne. The LS2 Annual Meeting brings together scientists from all nations and backgrounds to explore the large spectrum united under the umbrella of Life Sciences.