With a growing number of technologies, tests, antibiotic-resistant bugs, and epidemics, molecular diagnostics are more important than ever for a wide range of infectious diseases. Molecular Diagnostics for Infectious Disease, now in its third year at the Molecular Med Tri-Conference, will describe, discuss, and debate the benefits and challenges in the latest advances in molecular testing technologies and approaches. We will focus on the latest advances in next generation sequencing as the path forward for this technology, including implementation and reimbursement. We will address the latest in rapid diagnostics for point-of-care testing, as well as challenges in diagnosing sepsis and CNS, GI, and respiratory infections. Special attention will be paid to the diagnosis of C. Difficile and questions surrounding molecular versus toxin testing. This year’s antimicrobial resistance section will focus on bacterial identification and antibiotic resistance profiling. A special session this year will focus on the next era of diagnostics: artificial intelligence and data science approaches to infectious disease diagnosis. Join esteemed colleagues, service and technology providers, and peers to discuss these topics and more.