This Symposium will bring together those working in distinct disciplines such as cell and developmental biology, tissue biophysics, theoretical modeling, organoids and synthetic biology, and provide a platform to discuss and identify key approaches. This symposium aims to understand the mechanisms of self-organising properties of multi-cellular systems. One of the defining features of living systems is their capacity to break symmetry and self-organise to form reproducible shapes and patterns. However, the mechanistic understanding of this process remains a challenge as it requires a multi-disciplinary approach. This symposium will bring together those working in distinct disciplines such as cell and developmental biology, tissue biophysics, theoretical modelling, organoids and synthetic biology, and will provide a platform to discuss and identify key approaches and future collaborations. EMBL Heidelberg, Germany 11 - 14 Mar 2018 EMBO | EMBL Symposia promote scientific communication and collaboration in the European research area. They provide scientists with a platform to discuss and exchange ideas on forward-looking topics and new developments in the life sciences. Topics emphasise upcoming developments and the interdisciplinary nature of related fields. Jointly funded and organised by EMBO and EMBL – and complementary to their respective courses, workshops, and conference programmes – the symposia promote scientific communication and collaboration. All symposia are held in the EMBL Advanced Training Centre (ATC) in Heidelberg, Germany.

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