Mayo Clinic Radiation Oncology: Current Practice and Future Direction is intended to provide balanced and multidisciplinary discussion of contemporary cancer treatment using didactic lectures, panel discussions, and poster sessions. The course will cover several specific clinical areas including Breast, Prostate, and CNS cancers as well as Lymphoma and Sarcomas. The course will also address several important advances in the field, such as the use of hypofractionation, integration of surgery, new chemotherapies including immunotherapy and their integration into clinical practice. This course is designed for radiation oncologists, radiation oncology residents, radiation biologists, radiation physicists, dosimetrists, oncologists working in related specialties, radiation therapists, radiation oncology nurses, oncologic surgeons, radiation oncology administrators, diagnostic radiologists, and all other health professionals involved in the field of radiation oncology. Course Learning Objectives Upon conclusion of this course, participants should be able to: Discuss management strategies for PSA failure of prostate cancer Review surgical options of PSA failure Summarize the future of prostate brachytherapy Explain radiotherapy for early stage breast cancer List controversies in the surgical management of the axilla Discuss established and emerging systemic therapy for Hodgkin Lymphoma Review Hodgkin Lymphoma in pediatric patients Describe radiation therapy for Indolent Non-Hodgkin Lymphoma Explain the current practice of intracranial radiosurgery Review the target volume delineation in gliomas and sarcomas Discuss radiotherapy for chemo-sensitive sarcomas